A sizable portion of video game history is going to be rendered inaccessible to the average user within the next few years:
According to Eweek, Windows Vista will not be able to run 16-bit programs, so Windows 3.1 programs, and many DOS programs (most? all?) will cease to work once you install upgrade to Vista.
Apple’s switch to Intel chips also means the end of OS 9 support, so all your pre-2001 Mac games are not going to work anymore.
We will still be able to play old games in the future by running various emulators and virtual machines, but it will be out of reach for most users.
11 years from the release of Windows’95 to not supporting Windows 3.1 is a very short time in culture, but 5 years from the release of OSX to not supporting OS9 is the blink of an eye.
These are corporate decisions that could be reversed. Somebody should stage a campaign. Any takers?